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Actos Overview

Actos and Bladder Cancer

Actos (pioglitazone) is a drug developed by Takeda Pharmaceuticals for the treatment of type-2 diabetes, a condition where the body does not efficiently produce insulin and cannot effectively regulate sugar in the blood.

When the drug was first made available to the public in 1999, it was well received and quickly became popular among patients and doctors. Side effects from Actos were reported, however, and included increased likelihood of broken or fractured bones in women post-menopause, higher risk of congestive heart failure, weight gain, and swollen limbs.

In 2011 the FDA issued a warning addressing the results of a Takeda study indicating that longtime Actos users and those with the highest accumulative dose may experience a 40 percent increased risk of bladder cancer over patients taking other medications. The FDA mandated that information about the risk be added to the label of the drug and advised that Actos not be prescribed to people with bladder cancer or a history of bladder cancer.

Bladder cancer causes malignant growths in the urinary bladder. The condition can cause frequent urination, urinary tract infections and weight loss. Bladder cancer can recur, but advances in treatment have made bladder cancer manageable.

Actos Side Effects

eHealthMe, a Web site, analyzed the incidence of Actos side effects of Actos, and in 2013 released its findings, including this list of the most common side effects for patients who have taken the drug more than one year:

Among females 60 years old or older

  • Bladder cancer
  • Myocardial infarction
  • Weight increase
  • Cardiac failure congestive

Among males 60 years old or older

  • Bladder transitional cell carcinoma
  • Blood glucose increased
  • Bladder cancer

Bladder Cancer Symptoms

In many cases blood in the urine is the first sign of bladder cancer. There can be other signs, but some people will experience no symptoms at all.

  • Blood in the urine
  • Red color in the urine
  • Worsening urgency to urinate
  • Painful urination

How Can I File an Actos Lawsuit?

If you have taken Actos and have suffered a bone fracture or break or had cardiovascular difficulties after taking Actos, you may be able to sue Actos’ manufacturer or marketer.  Actos is produced by Takeda Industries and co-marketed by Eli Lilly & Co. Actos lawyers are offering free legal consultations to anyone injured by this drug.  If you are suffering after taking Actos- contact an attorney today!

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